12,867 research outputs found
Parametrization of the Driven Betatron Oscillation
An AC dipole is a magnet which produces a sinusoidally oscillating dipole
field and excites coherent transverse beam motion in a synchrotron. By
observing this coherent motion, the optical parameters can be directly measured
at the beam position monitor locations. The driven oscillation induced by an AC
dipole will generate a phase space ellipse which differs from that of the free
oscillation. If not properly accounted for, this difference can lead to a
misinterpretation of the actual optical parameters, for instance, of 6% or more
in the cases of the Tevatron, RHIC, or LHC. The effect of an AC dipole on the
linear optics parameters is identical to that of a thin lens quadrupole. By
introducing a new amplitude function to describe this new phase space ellipse,
the motion produced by an AC dipole becomes easier to interpret. Beam position
data taken under the influence of an AC dipole, with this new interpretation in
mind, can lead to more precise measurements of the normal Courant-Snyder
parameters. This new parameterization of the driven motion is presented and is
used to interpret data taken in the FNAL Tevatron using an AC dipole.Comment: 8 pages, 8 figures, and 1 tabl
Hawking radiation of a vector field and gravitational anomalies
Recently, the relation between Hawking radiation and gravitational anomalies
has been used to estimate the flux of Hawking radiation for a large class of
black objects. In this paper, we extend the formalism, originally proposed by
Robinson and Wilczek, to the Hawking radiation of vector particles (photons).
It is explicitly shown, with Hamiltonian formalism, that the theory of an
electromagnetic field on d-dimensional spherical black holes reduces to one of
an infinite number of massive complex scalar fields on 2-dimensional spacetime,
for which the usual anomaly-cancellation method is available. It is found that
the total energy emitted from the horizon for the electromagnetic field is just
(d-2) times as that for a scalar field. The results support the picture that
Hawking radiation can be regarded as an anomaly eliminator on horizons.
Possible extensions and applications of the analysis are discussed.Comment: 14 pages, 1 figur
Initial state maximizing the nonexponentially decaying survival probability for unstable multilevel systems
The long-time behavior of the survival probability for unstable multilevel
systems that follows the power-decay law is studied based on the N-level
Friedrichs model, and is shown to depend on the initial population in unstable
states. A special initial state maximizing the asymptote of the survival
probability at long times is found and examined by considering the spontaneous
emission process for the hydrogen atom interacting with the electromagnetic
field.Comment: 5 pages, 1 table. Accepted for publication in Phys. Rev.
Zero energy resonance and the logarithmically slow decay of unstable multilevel systems
The long time behavior of the reduced time evolution operator for unstable
multilevel systems is studied based on the N-level Friedrichs model in the
presence of a zero energy resonance.The latter means the divergence of the
resolvent at zero energy. Resorting to the technique developed by Jensen and
Kato [Duke Math. J. 46, 583 (1979)], the zero energy resonance of this model is
characterized by the zero energy eigenstate that does not belong to the Hilbert
space. It is then shown that for some kinds of the rational form factors the
logarithmically slow decay of the reduced time evolution operator can be
realized.Comment: 31 pages, no figure
B-mode polarization induced by gravitational waves from kinks on infinite cosmic strings
We investigate the effect of the stochastic gravitational wave (GW)
background produced by kinks on infinite cosmic strings, whose spectrum was
derived in our previous work, on the B-mode power spectrum of the cosmic
microwave background (CMB) anisotropy. We find that the B-mode polarization due
to kinks is comparable to that induced by the motion of the string network and
hence the contribution of GWs from kinks is important for estimating the B-mode
power spectrum originating from cosmic strings. If the tension of cosmic
strings \mu is large enough i.e., G\mu >~ 10^{-8}, B-mode polarization induced
by cosmic strings can be detected by future CMB experiments.Comment: 13 pages, 1 figur
Gravitational waves from kinks on infinite cosmic strings
Gravitational waves emitted by kinks on infinite strings are investigated
using detailed estimations of the kink distribution on infinite strings. We
find that gravitational waves from kinks can be detected by future pulsar
timing experiments such as SKA for an appropriate value of the the string
tension, if the typical size of string loops is much smaller than the horizon
at their formation. Moreover, the gravitational wave spectrum depends on the
thermal history of the Universe and hence it can be used as a probe into the
early evolution of the Universe.Comment: 29 pages, 4figure
Identification of novel clostridium perfringens type E strains that carry an iota toxin plasmid with a functional enterotoxin gene
Clostridium perfringens enterotoxin (CPE) is a major virulence factor for human gastrointestinal diseases, such as food poisoning and antibiotic associated diarrhea. The CPE-encoding gene (cpe) can be chromosomal or plasmid-borne. Recent development of conventional PCR cpe-genotyping assays makes it possible to identify cpe location (chromosomal or plasmid) in type A isolates. Initial studies for developing cpe genotyping assays indicated that all cpe-positive strains isolated from sickened patients were typable by cpe-genotypes, but surveys of C. perfringens environmental strains or strains from feces of healthy people suggested that this assay might not be useful for some cpe-carrying type A isolates. In the current study, a pulsed-field gel electrophoresis Southern blot assay showed that four cpe-genotype untypable isolates carried their cpe gene on a plasmid of ~65 kb. Complete sequence analysis of the ~65 kb variant cpe-carrying plasmid revealed no intact IS elements and a disrupted cytosine methyltransferase (dcm) gene. More importantly, this plasmid contains a conjugative transfer region, a variant cpe gene and variant iota toxin genes. The toxin genes encoded by this plasmid are expressed based upon the results of RT-PCR assays. The ~65 kb plasmid is closely related to the pCPF4969 cpe plasmid of type A isolates. MLST analyses indicated these isolates belong to a unique cluster of C. perfringens. Overall, these isolates carrying a variant functional cpe gene and iota toxin genes represent unique type E strains. © 2011 Miyamoto et al
Increasing the Receptor Tyrosine Kinase EphB2 Prevents Amyloid-β-induced Depletion of Cell Surface Glutamate Receptors by a Mechanism That Requires the PDZ-binding Motif of EphB2 and Neuronal Activity.
Diverse lines of evidence suggest that amyloid-β (Aβ) peptides causally contribute to the pathogenesis of Alzheimer disease (AD), the most frequent neurodegenerative disorder. However, the mechanisms by which Aβ impairs neuronal functions remain to be fully elucidated. Previous studies showed that soluble Aβ oligomers interfere with synaptic functions by depleting NMDA-type glutamate receptors (NMDARs) from the neuronal surface and that overexpression of the receptor tyrosine kinase EphB2 can counteract this process. Through pharmacological treatments and biochemical analyses of primary neuronal cultures expressing wild-type or mutant forms of EphB2, we demonstrate that this protective effect of EphB2 depends on its PDZ-binding motif and the presence of neuronal activity but not on its kinase activity. We further present evidence that the protective effect of EphB2 may be mediated by the AMPA-type glutamate receptor subunit GluA2, which can become associated with the PDZ-binding motif of EphB2 through PDZ domain-containing proteins and can promote the retention of NMDARs in the membrane. In addition, we show that the Aβ-induced depletion of surface NMDARs does not depend on several factors that have been implicated in the pathogenesis of Aβ-induced neuronal dysfunction, including aberrant neuronal activity, tau, prion protein (PrP(C)), and EphB2 itself. Thus, although EphB2 does not appear to be directly involved in the Aβ-induced depletion of NMDARs, increasing its expression may counteract this pathogenic process through a neuronal activity- and PDZ-dependent regulation of AMPA-type glutamate receptors
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